I've been following YouTube user PhortySiks for some time now, checking out his videos where he breaks down how to make certain synth sounds (mainly rave and dubstep type stuff). He's actually pretty talented at getting it close, and he uses all soft synths from what I can see. Here he is making the new Skrillex track's lead in Massive. This is a pretty great track and features Ellie Goulding. Compare the PhortySiks' to the original below. I tried this sound out on a standard analog synth, and you can get pretty close as well.